Heterochromia Iridium

Have you ever seen cats, dogs or even people whoose different eye colors? Or never see the character Yuna (Final Fantasy X, in which one side, the color of his eyes is different from the other side?. Now, Mbah Dukun Bagong, the modern shaman form medical and health information will explain of this eye abnormalities.

Definition
Heterochromia is a color difference on the individual, such as the eyes, skin and hair. Heterochromia of the eye called Heterochromia Iridium. So Heterochromia Iridium is a condition in which there are differences in the color of the iris in one eye (partial) or both eyes (complete).

Partial Heterochromia Iridium

Complete Heterochromia Iridium

Classification and Etiology
Heterochromia is classified primarily by onset: as either genetic or acquired. Although a distinction is frequently made the between Heterochromia That affects an eye completely or only partially (sectoral Heterochromia), it is Often classified as either genetic (due to mosaicism or congenital) or acquired, with mention as to whether the affected iris or portion of the iris is darker or lighter.

Congenital Heterochromia
Heterochromia That is congenital is usually inherited as an autosomal dominant trait.
Abnormal iris darker
• Lisch nodules - iris hamartomas seen in neurofibromatosis.
• Ocular melanosis - a condition characterized by Increased pigmentation of the uveal tract, episclera, and anterior chamber angle.
• Oculodermal melanocytosis (nevus of Ota)
• Pigment dispersion syndrome - a condition characterized by loss of pigmentation from the posterior iris surface and the which is disseminated intraocularly Deposited on Various intraocular structures, including the anterior surface of the iris.
• Sturge-Weber syndrome - a syndrome characterized by a port-wine stain nevus in the distribution of the trigeminal nerve, ipsilateral leptomeningeal angiomas (leptomaningiomas) with intracranial calcification and neurologic signs, and angioma of the choroid, Often with secondary glaucoma.
Abnormal iris lighter
• Simple Heterochromia - a rare condition characterized by the absence of other ocular or systemic problems. The lighter eye is typically regarded as the affected eye as it usually shows iris hypoplasia. It may affect an iris completely or only partially.
• Congenital Horner's syndrome - Sometimes inherited, although usually acquired
• Waardenburg's syndrome [9] - a syndrome in the which presents as a bilateral Heterochromia iris hypochromia in some cases. A Japanese review of 11 albino children with the disorder found That Had all sectoral / partial Heterochromia.
• Piebaldism - similar to Waardenburg's syndrome, a rare disorder of melanocyte development characterized by a white forelock and multiple symmetrical hypopigmented or depigmented macules.
• Hirschsprung's disease - a bowel disorder associated with Heterochromia in the form of a sector hypochromia. The affected sectors have been shown to have reduced numbers of melanocytes and Decreased stromal pigmentation.
• Incontinentia pigmenti
• Parry-Romberg syndrome

Acquired Heterochromia
Heterochromia That is acquired is usually due to injury, inflammation, the use of Certain eyedrops, or tumors.
Abnormal iris darker
• Deposition of material
o Siderosis - iron deposition within ocular tissues due to a penetrating injury and a retained iron-containing, intraocular foreign body.
o Hemosiderosis - long standing hyphema (blood in the anterior chamber) following blunt trauma to the eye may lead to iron deposition from blood products
• Use of Certain eyedrops - prostaglandin analogues (latanoprost, isopropyl unoprostone, travoprost, and bimatoprost) are used topically to lower intraocular pressure in glaucoma Patients. A concentric Heterochromia has developed in some Patients applying these drugs. The stroma around the iris sphincter muscle Becomes Darker Than the peripheral stroma. A stimulation of melanin synthesis within iris melanocytes has been postulated.
• neoplasm - melanomatous nevi and tumors.
• Iridocorneal endothelium syndrome
• Iris ectropion syndrome
Abnormal iris lighter
• heterochromic Fuchs iridocyclitis - a condition characterized by a low grade, asymptomatic uveitis in the which the iris in the affected eye Becomes hypochromic and has a washed-out, somewhat moth Eaten appearance. The Heterochromia can be very subtle, ESPECIALLY in Patients with lighter colored irides. Often it is most easily seen in daylight. The prevalence of Heterochromia associated with Fuch's has been estimated in Various studies with results suggesting That there is more difficulty recognizing iris color changes in dark-eyed individuals.
• Acquired Horner's syndrome - usually acquired, as in neuroblastoma, although Sometimes inherited.
• neoplasm - melanomas can also be very lightly pigmented, and a lighter colored iris may be a Rare Manifestation of metastatic disease to the eye.
Heterochromia has also been observed in Those with Duane syndrome.
• Chronic iritis
• Juvenile xanthogranuloma
• Leukemia and lymphoma

Central Hieterochromia

Central Heterochromia is an eye condition where there are two colors in the same iris; the central (pupillary) zone of the iris is a different color than the mid-peripheral (ciliary) zone.
Eye color is determined primarily by the concentration and distribution of melanin within the iris tissues; anything affecting Those factors may result in a difference of color being observed.
The human iris can be seen in a number of Various colors. There are three true colors in human eyes That determine the outward appearance: brown, yellow, and gray. The amount of each color an individual has determines the appearance of his or her eye color.
Eyes are displaying central Heterochromia Often Referred to as "cat eyes" Because of the appearance of a multi-colored iris. Central Heterochromia Appears to be prevalent in irises containing low amounts of melanin. Central Heterochromia does not label an eye as hazel. Because this is the outer ring of the eye is affected by central Heterochromia iris That's true color. A famous case of a person with central Heterochromia was Baroness von Rozsika Edle Wertheimstein, Whose daughter wrote: "She was a very beautiful woman ... She Had dark, dark brown eyes, but each eye had a purple ring to it, about a quarter of an inch of purple around these dark brown eyes.

Resource: http://www.answers.com/topic/heterochromia