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Laryngeal Papilloma

Inul Daratista, dangdut singer, came to Mbah Dukun,s house. She complained to mbah dukun about her voice. use laryngoscope direct methode, mbah dukun found something in Inul's laryng. what is that? it called Laryngeal Papilloma. Do you wanna know about Laryngeal Papilloma? just click options below.

1. Definition
2. Etiology
3. Histopatology
4. Clinical manifestations
5. Diagnose
6. Therapy and treatment (management)
7. Complications

Laryngeal papilloma is a benign proliferative squamous epithelial cell larynx which most often found. Papillomavirus is the type of tumor that develops rapidly, although not malignant. These tumors can migrate to the oral cavity, nose, trachea and lungs, but the most common location is larynx.

There are two types of laryngeal papillomas: one is the laryngeal papilloma juvenilis usually multiple and tend to be aggressive. The other is a solitary senile larynx papilloma and less aggressive but can develop into malignant.

The cause of laryngeal papilloma is a " human papilloma virus ' ( HPV ) types 6.11 which infect epithelial cells. It is estimated that the spread of the disease is present at birth from mothers exposed by " genital warts ".
In the normal mucosa cells adjacent to the papilloma, also contain viral DNA that can be activated recurrent lesions. Papilloma in children is more often multiple and recur than adults. While the papilloma in adults is usually single but it tends to become malignant with a specific subtype found that HPV 16.


Macroscopic : eksofitik lesions, such as cauliflower, gray or red and bleed easily. This type of lesion is aggressive and easily relapse, but may disappear  spontaneously.
Microscopic: showing a group of connective tissue stroma and blood vessels such as the fingers are coated with a layer of squamous epithelial cells or parakeratotik keratotic surface. Sometimes a picture appeared that bermitosis cells.

clinical manifestations
Initial symptoms are the form of hoarse voice phonation disorders, disfoni even afoni. If the papilloma is large enough can cause respiratory problems such as cough, shortness, and stridor inspiration. In children, the bias occurs misdiagnosis, because often show symptoms of hoarseness, stridor, and respiratory distress after failed treatment of severe asthma or bronchitis.

Found symptoms of hoarseness until afoni arise even respiratory distress. At the sound of crying children can appear abnormal. Found also a history of progressive hoarseness changes slowly, especially in patients who have a history of the parents had suffered Condyloma akuminata.
physical examination
Usually there is stridor on inspiration and direct laryngoscopy examination of the tumor that resembles the picture looks cauliflower, red, brittle, and bleed easily

Differential Diagnoses
1. Vocal cord polyp.
2. Vocal cord cyst.
3. Vocal cord nodules
4. bronchial asthma
5. bronchitis
6. laryngomalaise

Laryngeal papilloma therapeutic goal is to maintain the airway, maintaining voice quality and eliminates the mass of papilloma and prevent recurrence.
a. Surgery
Some techniques used include: tracheostomy, laryngofissure, microlaryngoscope and extirpation by forceps, microcauter, microlaryngoscope with diathermy or ultrasound, cryosurgery, CO2 surgical laser.
b. medical
Drugs used: antivirus, hormone ( diethylstilbestrol ), steroids, and topical podophyllin
c. immunologically
using interferon
d. photodynamic therapy
This therapy uses dihematoporfirin ether which are activated with the appropriate wavelength (630 nm ).

Post-operative care including total voice rest during the first week, spoke softly during the second week, and gradually to normal in the third week. To speed healing and prevent mucosal dryness is important given the cold mist inhalation (cool mist ) during the first week.

In general, laryngeal papillomas in children may heal spontaneously when puberty, but can be extended to the trachea, bronchus, and lung, believed to tracheostomy or extirpation due to action is not perfect.


Prognosis is generally good, early diagnosis and appropriate treatment is a factor thought to affect recurrence. The cause of death is usually due to spread to the lungs.


  1. ini penyakit yang menjadi pembunuh nomor 1 bagi wanita. Thx infonya :))

  2. wah serem juga ya....mbah... ini kunjungan balik lho :)

  3. kunjungan balik nih mbah,,,

    serem banget maen ke sini,
    tapi makasih atas infonya....

  4. Artikel yang menarik sob, lebih baik mencegah daripada mengobati.

  5. Pasiennya sampai artis terkenal ... Semoga Mbah Dukun Bagaong makin sukses ....

  6. @kaki kecil: pembunuh paling banyak pada wanita tuh kanker servix gan ... makasih komengnya ya
    @LOvelydebz: wah masa wajah ane serem sih? hehehehe
    @Agung Ngurah: ya donk gan....
    @ Campuran: ya donk mantab

  7. Serem juga penyakitnya.... mudah2an gak sampe kena keluarga saya... artikel yang bagus gan....

  8. Kunjungan balik Mbah...

    Iiih kenapa sih jika mampir ke sini slalu disuguhi gambar2 yg suerem2. he he he...
    Nice posting Mbah...

    Salam 'Sehat'

  9. seremmmm
    kunjungan balik nih mbah... ^_^

  10. can this disease infect man?? hmm, I think it's not good, how to treat it??

  11. Saya sudah follow, terimakasih sudah berkunjung.. Bisa minta informasi tentang penyembuhan penyakit hemoroid? kirim ke email saya. Terimakasih :)

  12. wih serem banget.


  13. Kenikmatan terdapat pada tubuh yang sehat..betul tidak..??

  14. @ Ladida: ya bisa donk infects ke laki-laki
    @ Ririn: Hemoroid akan segera dipostingkan
    @ Pakde Sulas: mmm kaya gendruwo aja serem
    @ Bareha: betul tuh gan
    @ Vania : okey i follow u, would u exchange link with me?

  15. wahh,, serem banget mbah.. kunjungan balik lho ini :D

  16. Masyaallah, penyakit manusia kian beragam dan sulit disembuhkan iyaaa... Aduh, kuingin dipanggil Allah SWT tanpa harus mengalami sakit lebih dahulu... Amien


  18. Request : yang berhubungan dengan jantung di posting ya dokter.
    Terima kasih

  19. :: Visiting here with smile, nice greetings...^_^

  20. serem saya ngeliatnya. hihi... nice info mbah dukun :)

  21. I was horrified to see her


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