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DOWN SYNDROME


 DEFINITION 

two days ago Mbah Dukun Bagong visit his hometown, he met his old friend, he saw his friend's daughter. her face look freaky, like mongoloid face, whats wrong with her?

Down Syndrome, Trisomy 21 or Mongolism, was first described by Dr. Langdon Down in 1865. At that time, the diagnosis of the syndrome was based solely on physical findings. Down syndrome isn't a disease. Down Syndrome is a genetic condition. As the word syndrome implies, it is a collection of common characteristics that is evident not only physically, but also by a degree of learning disability.

CONDYLOMA ACUMINATA



DESCRIPTION

Genital warts or condyloma acuminata are warty growths that can be found on the labia, vagina, and cervix as well as in, and around the anal area, the external urethral opening or in the bladder. Men may also have condyloma on the penis and scrotum, in and around the anal opening, and in the urethra. Condyloma are caused by the Human Papilloma Virus (HPV).

GONORRHEA

DEFINITION

Gonorrhea is a disease of sexually transmitted infections (STI) caused by the bacterium Neisseria gonorrhoeae, gram negative bacteria diplokokkus who made man as the intermediary. For several centuries, a variety of names have been used to describe infections caused by N.



MENINGOCELE


DEFINITION
 Meningocele is considered less severe that myelomeningocele because the spinal cord doesn’t leave the protective bone tube. There is still a sack on the back, but the nerves of the spinal cord are not in it. The nerves remain protected and therefore are not as badly damaged. A person with Meningocele will usually have better physical development and bowel and bladder control.


MYELOFIBROSIS

DEFINITION

Mielofibrosis is a disease in the bone marrow in which collagen form a  fibrosis tissue in cavum marrow. This happens because the uncontrolled growth of blood cell precursors, which eventually led to the accumulation of connective tissue in the bone marrow. Connective tissue that forms blood cells which ultimately lead to dysfunctional form. Our bodies are aware of this, and tries to compensate by sending a signal to hematopoietic extramedulare organs, namely liver and spleen to produce new blood cells. But the blood cells that eventually produced by these organs is still not functioning properly and the body finally experiencing anemia. 

Idiopathic thrombocytopenic purpura

DEFINITION

Patient asks to mbah dukun: "Mbah, my name is Painem, im from Belgia, i have a problem. my son's legs frequently bruising, red spots appear, these has been about 6 months, intermittent, sometimes accompanied by fever, DHF-like disease. Would you tell me what is that?
Mbah Dukun anwers:

ITP, primary immune thrombocytopenia (also called immune (idiopathic) thrombocytopenic purpura), is an autoimmune disease. In autoimmune diseases, the body mounts an immune attack toward one or more seemingly normal organ systems. In ITP, platelets are the target. They are marked as foreign by the immune system and eliminated in the spleen and sometimes, the liver. In addition to increased platelet destruction, some people with ITP also have impaired platelet production.

Chronic Myelogenous Leukemia


 Definition
Chronic Myelocytic leukemia (mieloid, mielogenous, granulocytic, CML) is a disease in which a cell in the bone marrow turn into malignant and produce a large number of granulocytes (a type of white blood cells) are abnormal . When this happens, infectious anemia, or bleeding easily occurs. CML seldom attack individuals under the age of 20 years, but the incidence increases with age.

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